 Violet (Milla Jovovich) lives in a totalitarian world in the future, ruled by Daxus (Nick Chinlund). Once she was a human and the assistant of his husband, a scientist, murdered by the police forces of Daxus, who has turned into vampires a considerable part of the human race just to enlarge his forces. Violet has the task of rescue a secret weapon: a boy named Six (Cameron Bright). After knowing the real intentions of this people with the boy, Violet takes him away and she ll be chased by Daxus, because Six carries in his blood a rare cure, which could heal Violet and all the vampires, in this kind of mix of Matrix, with Aeon Flux and Kill Bill.