 In Prague, Czech Republic, the single mother Helena is seduced by a successful handsome man and travels with him to spend a weekend in Vienna, Austria; in Kiev, Ukraine, the sixteen-year-old Nadia is selected by a model agency and travels to the United States with the other selected candidates; in Manila, Philippines, the twelve-year-old American tourist Annie Gray is abducted in front of her parents. In common, the girls become victims of a powerful international network of sex traffickers leaded by the powerful Sergei Karpovich. In New York, after the third death of young Eastern European prostitutes, the obstinate Russian-American NYPD agent Kate Morozov convinces the Immigration and Customs Enforcement Chief Bill Meehan to hire her, promising him that she would fight against this type of crime and that he would not regret.