 When his old friend, the laboratory engineer Tom Gruneman (Robert Mili), vanishes, detective John Klute (Donald Sutherland) is hired by Tom s colleague Peter Cable (Charles Cioffi) to search for him. The unique lead is an obscene letter written by Tom to a call-girl in New York called Bree Daniels (Jane Fonda), and Klute moves to the Apple city to investigate the disappearance of Tom. Klute blackmails Bree to help him to find other prostitutes that might have been with Tom using some tapes of her phone calls that he had secretly recorded. They realize that some is stalking Bree, while Klute falls in love for Dress, and she has some sort of feeling that she can not understand for him.