 Sherlock Holmes is drawn into the case of Jack the Ripper who is killing prostitutes in London s East End. Assisted by Dr. Watson, and using information provided by a renowned psychic, Robert Lees, Holmes finds that the murders may have its roots in a Royal indiscretion and that a cover-up is being managed by politicians at the highest level, all of whom happen to be Masons. Homes races to save the life of Annie Crook who has been forcibly incarcerated in an insane asylum and that of her friend Mary Kelly, in whom she has entrusted her secret.