 When battered prize-fighter Lee Burke (Dick Foran) is taken to the West Side hospital, nurse Katherine MacDonald (Helen Mack) leaves her romantically-inclined patient, wealthy attorney John Dodge (Edmund Lowe) to take care of Burke. She discovers that Burke was doped by his handler, Churchill (George McKay), on instructions from gambler Joe Largo (Leon Ames) so the latter can win a $5000 bet from Burke s manager Slice Cavanaugh (Paul Hurst.) Largo orders henchman Larry Carson (Horace MacMahon) to bump off Churchill to keep him from talking. Katherine talks Burke into quitting the ring and Dodge belittles the ex-boxer by getting him a job as a bellhop. Cavanaugh, desperate for money, calls Burke yellow and when Burke happens upon the scene where another Largo henchman, Smiley (Paul Fix), has killed the manager, Burke is tried for the murder.