 A young man named Sean Jones witnesses vicious and powerful mobster Eddie Kim brutally murder a prosecutor bent on putting the crime mogul behind bars. Soon Kim s men raid Jones  house and attempt to kill him, but are stopped by Nelville Flynn: an experienced FBI agent who convinces Jones to fly to LA to testify against Kim. Aboard the flight are an obnoxious British businessman, a famous hip hop star, an anxious man with severe flight anxiety and his wife, a young woman and her dog, and a ticking crate full of vicious and venomous snakes unleashed by an assassin to bring down the plane along with the witness to Kim s brutal murder. Can the passengers come together to survive or will Kim s plot succeed.