 Scout and wagon-train guide Kirby Randolph (John Payne) hates all Indians, particularly Kiowa Chief Satank (George Keymas), whose massacre of an entire wagon-train of settlers led by Kirby, has led to his ostracism and neither he nor his pal Sam Beekman (Slim Pickens) can get jobs. Aurelie St. Clair (Faith Domergue), who owns half of an ammunition shipment for sale in Santa Fe to Mexican insurrectionaries, protests when he partner Jess Griswold (Rod Cameron) hires Kirby and Sam as guides. When Kirby saves them all from a wild horse stampede instigated by Satank, she changes her mind and she and Kirby fall in love, although Kirby does not realize she is half-Indian. Jess, who is also in love with Aurelie and wanting to get rid of Kirby, sends his servant Chavez (Anthony Caruso) to Satank offering to deliver Kirby to the Chief in return for safe passage for the wagon train. But, Satank plans to get both Kirby and the wagon train.