 "The Brookdale Institute" is a mysterious, little-known hospital for the criminally insane (a fact which is kept on a need-to know basis). Brookdale has another, more lucrative facet; a safe harbor for the chronically drug-addicted rich and famous, especially the sons and daughters of the above, whose families have tried everything. "The Institute" is also for the once-famous, who, having bottomed out, also have no where else to turn but Brookdale. Investigating possible health code violations, "Jennifer/Samantha", ( Sara Downing (I) (qv)), a career-driven reporter for "The Philadelphia Enquirer", checks in under the guise of a patient, in hope of getting a hot story. Unbeknownst to her, the real scoop is much more awesome then even she could write about, should she live to tell. Brookdale is infested with super-intelligent, supernaturally empowered killer rats, a by-product of forgotten experiments conducted by "Dr. William Winslow" ( Ron Perlman (qv)), the Chief Psychiatrist at Brookdale. Winslow had abandoned the experiments long ago, however ex-patient/caretaker, "Ernst" ( Michael Zelniker (qv)) has developed a symbiotic, telepathic relationship with the rodents, and they thrive off of each other. As patients mysteriously disappear, and the body count mounts, even The Exterminators, RatMaster General "Hans" ( John Paul Young (qv)) and his assistant, "Jim" ( Adam Gierasch (qv)) are no contest for the awesome force of this hybrid rodent strain.