 Joe (Joe Pesci) and Gus (Danny Glover) are established early on as two of life s losers. As children, they are shown in opening sequences blowing up an industry as they toss a cigarette in an open pipe. Years later, as adults they get to go on a fishing vacation that you know has to go wrong. First, they are conned out of their car keys by a con man killer (Nick Brimble), who preys on older women. As they give pursuit, they team up with two young women (Rosanna Arquette, Lynn Whitfield) who are also after the killer who took all of Arquette s mother s jewelry & money. Many disasters later, the two are faced with the killer and all of his loot. Willie Nelson makes a brief appearance as a philospher fisherman that the two amateur fishermen worship.