 Thirteen years later Mrs. Garrett s "girls" have all grown into successful, independent women. After a stint in the Peace Corps with her husband, a widowed Mrs. Garrett is heading back to America, ready for a new life and new romance, and also looking forward to seeing the girls again. Blair is wealthier than ever, after building a hotel empire with her husband, Tad. But she suspects he is having an affair. "Tootie," now preferring to be called by her real name, Dorothy, has forsaken her acting hopes to host her own talk show. Natalie is a dedicated TV news producer, juggling an active love life with a frenetic work schedule that takes her all over the world. Jo, ever the free spirit, is a devoted cop, wife and mother. It s been years since Natalie has had a Thanksgiving back in America, so she s talked all the girls and Mrs. Garrett into spending the holiday together back in Peekskill, NY. When Jo is unable to attend the reunion, her teenage daughter, Jamie, and husband, Rick, come instead. They re all in for a surprise when Natalie s not one but two boyfriends unexpectedly show up at the reunion. Trouble soon starts, as both men compete for Natalie s attention and exclusivity, so it s up to the girls to help solve Natalie s predicament.