 Johnny Longo is a hopeful boxer who spends the night with Rose, a prostitute who has secretly used her racket connections to further his career. Johnny is up for a role on a local TV series playing a boxer co-starring Rita Roman, a once-famous actress who is now addicted to heroin. Johnny and Rita do not get along at all because of their constant fighting which upsets their acting rehearsals and Johnny s training schedule. Meanwhile, Rose, jealous over Johnny s career, plots with Rita to get him off the TV show by having him take LSD at a party, not realizing that the affects are more than both women will anticipate.