 Tyler Moore is the average guy who just can t seem to catch a break, especially when it comes to love and relationships. His three best friends, Allison, Elizabeth, and Erin, all see him as just that, the "best friend". Can Tyler survive the terrors of a celibate life as he struggles to become the man he thinks women want him to be? It s a mix of heartbreak and laughter as he s stuck being One of the Girls.