 Bill (Leary) wakes up from a coma in a hospital ward, raving about tissue regeneration experiments, final injections, organ transplants and having been cryogenically frozen. Battling flashbacks of his father s death and a car crash, occasional hallucinations and fits of rage he tries to piece together his own history with the help of Ann (Hope Davis), a lonely medical psychologist sent in to evaluate whether he should be released. In their confrontational, sexually-charged sessions, Bill flip-flops between pitch-perfect self-diagnoses and his paranoid bio-tech fantasies, but slowly begins to heal. But things are not what they seem.