 Garfield (voiced by Bill Murray), who competes with a dog named Odie for the affection and attention of their human master, Jon Arbuckle (Meyer), when Odie is introduced into their home much to Garfield s disgust. When Odie runs away, he gets picked up by a mean dog trainer, however, Garfield feels responsible, so he gets off his favorite spot and gets into action to rescue his fellow pet... (Jennifer Love Hewitt plays Liz, Garfield s veterinarian and romantic interest; Cannon plays a "city mouse" who helps Garfield in his search; Messing voices Arlene, Garfield s girlfriend)