 While traveling on the road with his wife Lindsay (Christine Lahti) and his daughter Regina (Alicia Silverstone), Hatch Harrison (Jeff Goldblum) has a car accident, hitting a truck and falling with his wife in a river. He dies for more than two hours, but the specialist Dr. Jonas Nyebern (Alfred Molina) successfully brings him back to life. Hatch has some weird premonitions and becomes able to see through the eyes of the psychopath serial killer Vassago (Jeremy Sisto), a young man that killed his mother and his sister and committed suicide and was also brought back to life and now is killing young women and teenagers. When he foresees that Vassago is trying to capture his daughter, Hatch tries to find the criminal first, in spite of Lindsay, Regina and the detective in charge of the investigation believe that he needs psychiatric help.