 Stony Brooke (Robert Livingston), Rusty Joslin (Raymond Hatton) and Rico (Duncan Renaldo), known as The Three Mesquiteers, return to Oklahoma at the close of the Spanish-American War, and are concerned that some of their wounded buddies have no prospects for a satisfactory future. When the government offers preferred homesteads in the newly-opened Oklahoma territory to war veterans, they send word for their pals to join them there. Once ther, the veterans meet a hostile reception as the cattlemen resent the influx of "nesters" and are determined to drive them out. Mace Liscomb (William Ruhl) and his brother Orv (Harold Daniels) plan not only to drive out the homesteaders, but to also doublecross the cattlemen and gain exclusive titles to the range lands for themselves. Stony and his pals eventually show the honest cattlemen that there is room for the settlers and that both are fighting a common enemy.