 Letitia "Tish" Carberry (Marjorie Main), an eccentric New England spinster, lives with her nephew, Charlie Sands (Lee Bowman), and her two cronies, Aggie Pilkington (Zasu Pitts) and Lizzie Wilkins (Aline MacMahon), live in a near-by boarding house. Cora Edwards (Susan Peters) also lives at the boarding house and is in love with Charlie, who, however, loves Katherine "Kit" Bowser (Virginia Grey), the daughter of Judge Horace Bowser (Guy Kibbee). Tish and her cronies promote a romance between Cora and Charlie, but Cora decides it is Theodore "Ted" Bowser (Richard Quine) she loves and they are secretly married before Ted leaves for a training school in Toronto, learning to ferry planes to England. Charlie and Katherine also elope secretly. Cora, anxious to join Ted, borrows money from the church organ fund and leaves, telling no one where she is going. Tish takes the blame for the shortage. Cora raises the money to repay Tish and goes to the post office, while Ted is on a flight. Before she mails it, she opens a letter she received from the Canadian government announcing Ted s loss at sea. She faints, is taken to the hospital and gives birth to a boy, and dies. The only clue to her identity is the letter addressed to Tish. She arrives, decides the baby is Charlie s son, declares herself the grandmother and takes it home. Once there, she and her cronies take care of it in a rented cottage and she now claims it is her own. As a result Charlie, not knowing why she makes such a claim, has her put into a sanitarium for mental cases, and he and Katherine take the baby and plan to send it to an orphanage as Katherine does not realize it is her own nephew.