 Once upon a time... it is a time of trouble is Mexico. The Mexican president has declared war on the Barillo drug cartel, who has plans to fight back by backing a coup by General Marquez. Agent Sands of the CIA is in the middle of it all trying to make sure Marquez do NOT succeed... by forcing El Mariachi himself out of retirement... El Mariachi, after the death of his wife and daughter, no longer wishes to fight, but he may not have a choice. At Culiacan, Barillo and Marquez have set a trap for the president, and Sands want El Mariachi to take out Marquez after the coup. El Mariachi called upon his two brothers for the final showdown... To save the revolution. Who will remain standing at the end?