 The two Beaudine brothers refuse rancher Hatcher s offer to go on his cattle drice but change their minds when he is shot. So they head out with six other riders, a cook and a recuperating owner heading 1500 cows towards Colorado 1000 miles away. Along the way they will face accidents, Indians, two of the riders aiming to rustle some of Hatcher s cattle and flee, squatters demanding money, a stampede, and a lack of water.